FWIW, my friend and I took all of our CC handguns to the range the other day.
We both shot our LCR's, Glock 43 and 26, and Taurus PT111 G2 just fine. Surprisingly, we also both shot my P3AT quite well.
I was disappointed to find that I've become spoiled. The rough DA triggers of my two Taurus 85's and my CA Bulldog made for some iffy groups. I used to shoot them okay, but I've apparently been shooting handguns with better triggers too often in the past few years and can't shoot the stiff ones that well anymore.
Still, I ended up feeling good about the whole thing. I can get the LCR out of a cargo pocket, the P3AT out of a breast pocket, or a small 9mm out of an OWB holster quickly, and empty any of them rapid-fire into a fist-sized group with no problem at seven yards. Sure, I'd be better armed with a full-sized service pistol and a bunch of spare mags, but with good tactical awareness I feel decently armed with the handguns that I normally carry.
I'm going to have to practice with the rougher-triggered snubbies regularly if I decide to start carrying any of them again. The sweet trigger on my LCR has spoiled me something fierce. (It doesn't hurt that the previous owner also put a nice fiber-optic sight on it.)