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I shot this eland with cz-550 in .375 H&H in Africa and the same rule goes if you wound it you bought it, so I opted to use the .375 so even with a marginal hit I had better chance of getting it. this eland was shot very close(maybe 60-70 yards) in heavy brush and I was glad I had chosen the 375.
It looks like a neck shot? That should stop him pretty good.
I bought a .375 H&H when I returned from Africa. After shooting it a dozen times, I put it away .. too much gun for me. If I used it, I would flinch and wound something with it. I could do much better with a 7x57 and premium bullets.