I'm just going to leave this here and see what happens. I'm kind of surprised it hasn't come up in this thread yet.
"There are two key elements to the .460 Rowland® concept. The first is a sharp increase in cartridge maximum pressure over the .45 ACP and .45 Super. Maximum Average Pressure is: 45 ACP (21,000 PSI), .45 ACP +P (23,000 PSI), .45 Super (28,000 PSI),
.460 Rowland® (40,000 PSI)."
"The Ruger Blackhawk and Smith & Wesson Model 25/625 can also be chambered to fire the .460 Rowland®."
https://www.460rowland.com/about/
Clark .460 Conversions
DESCRIPTION PRICE
Convert .45 ACP Ruger® Blackhawk® to shoot .460 Rowland Ammo $100.00
Convert S&W® 25/625 (.45ACP) to shoot .460 Rowland Ammo $100.00
https://clarkcustomguns.com/gunsmithing-service/clark-460-conversions/
I wouldn't do it to my 625, but apparently some pretty knowledgeable people are comfortable with it.