I used to shoot a pile of 50 grain Blitz bullets before groundhogs went on the endangered species list here in WV,and they weren't the most accurate bullets out there.I shot them in 222,223 and 22-250,and they all had fliers.I eventually started shooting the 52 and 53 grain Matchkings and they were a lot more consistent.I didn't see what twist rate you're running in your Fireball,but my experience with 22 cal. bullets has taught me that it can make a big difference.I have a 223 that's pretty accurate,usually 5 shots in the .2's and .3's at 100 yards.It's a 9 twist,and it really shines with 69 grain tipped Matchkings.With the current shortage of everything,I decided to save my remaining TMK's for competition and wanted to work up a load that used the 52 grain match bullets that I have plenty of.The groups I shot with them resembled what you're getting,probably a bit worse.I tried several things but it was a no go.I have the headspace on that rifle very tight.A standard full length die/shell holder gives a tiny bit of shoulder bump,but I neck size with a Lee collet die,and doing that has helped with my runout,and it's a simpler setup that a bushing die/mandrel setup.I used to fight bullet runout a lot in this rifle when I was using the Lee seating die that came with the collet die,and it was bad.I would often have one or two out of twenty that would exceed .010".I have a Hornady concentricity tool and I would try to straighten them with the screw thingy on the tool,thinking that if I got them straight they would shoot better.22 caliber bullets in unturned brass don't like to be pushed around,and I was making a bad situation worse by trying.I spent a few dollars on a L.E. Wilson seating die,and it was all I needed for runout prevention.I recently seated 10 rounds with the Wilson die and 10 rounds with the Lee die,and measured the runout and shot what the two dies produced in a head to head comparison.The worst round for the Wilson die was .002.The Lee die had one that was .009 and one that was .011.The two 10 shot groups were mostly the same size and shape,except for a couple of fliers on the Lee die,which were about half an inch or so out of the group.I think a few thousandths will still shoot well,but when you get over .005,bad things will happen.The runout rabbit hole can go a long way and cost a lot of money,sometimes with no improvement on how a rifle shoots.Make sure the bullet and the twist rate are ok with each other and maybe try a chamber seating die before you burn up a bunch of money,and maybe try a simpler sizing method.