Seems to be one of those problems for which there isn't a perfect solution.
Personally, I don't care about what other people might think. They can either be"cool"
about me carrying a weapon, or they can be cool
towards me. If they don't like it, then I figure maybe they don't have the best of intentions and I would just as soon let them know that I am not to be messed with. Anyway, where I go I am likely to see more bears than people.
I don't like having the gun on the backpack belt because I want it on me at ALL times.
What I got by with was carrying OWB on my leather jeans belt in the 1.00-2.00 o'clock position rather than my usual 4.00 o'clock behind the hip. Anyway, just far enough forward that the grip doesn't bang or catch on the packframe. Ran the backpack belt between the holster and my jeans, around my hips below my jeans belt as per usual. A crossdraw setup might work as well or better, as the grip would be pointed away from the packframe.
I think the best rig might be one of those "tactical"
thigh holsters that would ride below all the backpack rigging and would still be readily accessible. But I have only seen those made for semi-auto pistols, not a large frame revolver.
I've also wondered about those large cargo pant pockets for concealed carry in a similar position. Some of the old cowboys carried their "hogleg" in a pocket on their chaps rather than a belt holster. But I am not into buying a $50 to $80 pair of pants just to go backpacking.
My kids got a couple of those miniature ("hobbit"
) horses, and it sure got me to thinkin' about training one of those to pack. They don't eat like a big horse, and you could almost always find enough grass for them. Then I could get out from under the dang backpack altogether
Just have to train them to load and ride in the back of the pickup.