A gun that points naturally is a keeper, especially for SD scenarios. So that is a keeper.
Everyone is built differently so how it fits into one person’s hands will not ring true for another person. I find S&W M&P, Glock, S&W 640/442, Kimber K6S, CZ, S&W revolvers, P365, and Ruger Redhawk/GP100 revolvers/Mark Series fit me well. The Ed Brown 1911 commander size fit me perfectly, as well.
My FN Five Seven, Desert Eagle 44 Magnum, and Walther PPK/S do not, but they’re not for SD.
Other pistols I have owned that didn’t fit me well were the Beretta Nano, 92FS, Beretta PX4, Springfield XD/XDM, Ruger LCR, and HK 45C/Mark23/USP.
But of all of these that work one handed are Glock, Kimber K6S and S&W 442/640.