I don't have exactly the experience you're looking for, but something kind of related.
For the past 23 years or so, my centerfire revolvers were limited to the following that I owned for the duration (I've fired a lot of other revolvers belonging to friends and acquaintances, but only owned these two):
1982 model Smith & Wesson 686 6"
1981 model Colt Trooper Mk III 6"
Then a few years ago I bought a 1985 model Smith & Wesson 67-1 with 4" barrel.
I always liked the 686 better than the Trooper because it was just so much smoother in operation (single action and especially double-action) and just felt better to me, and fit my hand better. I have three friends/acquaintances with 6" Colt Pythons and I do not find them to have as good an action as my 686, or overall to feel as good in my hand. I have lightened the springs on my 686, but it is a work of art in terms of action and trigger pull, IMO (outstanding 2.3# S/A trigger pull, 6.5# D/A with no stacking or hitches, unlike the Trooper). I just love that handgun.
The 67-1 is also a very nice gun, a good size for handling and shooting, but it's not as sweet when it comes to actual shooting as the 686. The action isn't as good, but it's a great shooter as well, .38 Special only, of course.
Despite having owned the Trooper for so long and having some attachment to it, I've recently sold it and bought a pristine 4" Smith & Wesson 586 from the 1983 time frame. It's all stock at the moment, but I'll correct that soon.
I admire the Colt revolvers but I think Smith & Wessons just suit me better.