I was a co-worker to the individual the AlaDan mentioned.
I too doubted the .22cf's for deer until I used them.
My first experience with the .223 was unacceptable, but the reason was obvious. I used the Remington factory 50gr PHP which is a very explosive bullet on small varmints. It left very shallow surface wounds on the deer I shot with it.
Subsequently, I've used 55gr or heavier bullets in the .223 and later in the .22-250.
For personal reasons, I prefer the .22-250 to the .243. I've had quite a few bullet failures with the .243 and spent many hours trying to locate either deer I shot with it, or that others shot with it. (It was the darling cartridge of a number of deer poachers I delt with in my career, notably in the Remington M742 rifle). Many trophy class deer were hit and found hundred of yards away from where they were shot and lost by the poachers. Usually it was the circling vultures that resulted in locating the "evidence". Shot placement of course is equally important with the .243 as is the .22cf's....
I use primarily the 60gr Hornady Soft points. The 63gr Sierra is excellent, too but is a more expensive bullet and dosen't have the b.c. of the Hornady bullet. (bought a large quantity of the 60gr Hornady "blems", so still have a lot of the 60's on hand) My rifle has a 1/14" twist so dosen't do well with bullets heavier than 60gr, the Sierra 63gr semi-point being the exception. My .223 however satisfactorily stabilizes the 65gr Sierra Game King which I consider to be the best available deer bullet for the .22cf's.
Bonded, monolithic bullets, ect. just aren't the anwser to my thinking. If the bullet dosen't expand, it won't be any different than a FMJ. I've never recovered a 55gr or heavier soft-point from a deer anyhow...... I also never used or felt the need for the 60gr Nosler Partition, or any of the Barnes X, triple shocks, ect.
A well placed 55gr or heavier soft-point bullet from the .22-250 is a sure killer on our smaller whitetail deer. If I was hunting in the mid-west such as Kansas, Nebraska, ect or mule deer, I wouldn't use the .22cf's.
My next jump is to the .25's. My favorite being the .257Roberts. It has just killed everything I've pointed it at with no exceptions or alibi's.