24.2gr IMR4895, 60gr VMax, 2.25 OAL (used to do 2.26), Rem or Win Brass, Fed SR Primer.
I get 2600fps out of a 16" barrel with 1x9 twist. I shot a 5/8" 5 round group at 100 yards this past weekend. Usually I do 3/4". My rifle has the stock 2 stage trigger, and it's kind of clunky. I've got a Chip McCormick that I'm planning to install. I'm thinking I'll be sub 1/2" after that.
Since most of my Varmint hunting is at night, ranges don't normally exceed 100 yards. Not counting the buck fever I got on a coyote at 200 yards one night a couple months ago, I haven't missed a critter yet with this load. I should have tried to coax that dog in closer, but for some reason, I got antsy and fired. Yanked the snot out of the trigger. Result was predictable.
I also have a 50gr VMax load that's a little hotter but just as accurate. Everything the same except the bullet weight and powder increased to 25.2gr IMR4895. I get about 2850fps out of the muzzle on this load.