Why is a blowback action a disadvantage for that sort of weapon?
1) Straight blowback will have a more pronounced recoil than a locked action as more reciprocating mass is required to keep the case in the chamber until pressure has dropped
2) More mass is a disadvantage in itself. Ounces make pounds. Pounds make pain.
3) Especially in suppressed weapons, straight blowback weapons put more gas in the shooters face.
True, although, with a weapon zero'ed at 100 yards, if my calculations are correct, at 200 yards, you're only looking at a difference of about 2 inches in elevation and 40 ft. lbs. of energy
Back of the envelope SWAGs would tell you that a slender, pointy, boat tailed shape will have significantly less drag than a fat, blunt, flat based shape.
But, since ballistics is a funny animal...
Hornandy's free calculator, with given BC's for Hornandy bullets gives:
10mm, 1000fps, 200gr, .199 BC - drop of 40 inches at 200 yards when sighted at 100 yds, velocity of 846 fps, energy of 318 ftlbs
.30 cal, 1000fps, 200gr, .597 BC - drop of 36 inches, velocity 939, energy 391
The 10mm has 20% less energy than the BLK at that point... which is concerning since you are already limiting yourself to subsonic velocity and wont see much damage due to shock.
Even at 100 yds, the 10mm has 10% less energy (416 vs 370 ft lbs).
The above was chosen to highlight the effect of BC ONLY on the ballistics. Going to hornandy's expanding subsonic 300 blk ammo (
https://www.hornady.com/ammunition/rifle/300-blackout-190-gr-sub-x-subsonic#!/), we see numbers in the same ballpark as above, but with an expanding bullet vice a target bullet.