Looks like it's a pretty overwhelming consensus that H110/W296 is the way to go.
yep , I think most of use knew that , but thanks , and those are all good in 41mag and 44mag, I use Nosler HP and Hornady XTP's in 44mag's , and they are good in rifles , the OP wants a good deer load for a S&W 357mag , and my first hand experience is that a XTP HP in my S&W 19-5 357mag with a 4" barrel just don't do as good of a job as I'd like to see ,Just a note, all those pointy bullets with plastic tips are actually HP bullets and they are extremely popular hunting bullets like the AccuBond, Ballistic tip, A-Max, V-Max, BlitzKing and a whole bunch more...
Do NOT use a 125gr bullet on deer. The Hornady 158gr XTP bullet is about as good as it gets with a jacketed bullet for deer hunting in the .357 Magnum.
Don
What about the 140gr Hornady FTX bullet out of a .357 mag revolver?
If you use FTX bullets, make sure to trim down your Brass. Due to the length of the ogive, cases need to be trimmed to 1.240" in order to match the connelure for crimping and be within spec OAL.
Recited from "Hornady Handbook of Cartridge Reloading 8th Edition."