I looked at the S*w and the Taurus offerings. For me it's just too big to conceal. That's in my screwed up state, and not using my custom shoulder rig.
As long as it's freezing, I could carry one, but, why stop with a .44 Special?
Skeeter and Keith picked the .44 because it had thicker cylinder walls, and was stronger, due to the smaller case diameter.
That said, in this day and age, a number of .45 caliber guns can be had with
wall strong enough to push out the 25k range loads for the .45 colt.
If this is a house gun, then the ability to conceal is irrelevant. If it's a house gun, then something big, and heavy would be my choice, in .44 Magnum, or .454 and you can load to your hearts content.
If I can get to it, or the situation calls for it, my house gun is a Mosin Nagant M44. If I can't, there is something to be said for a high powered
hand gun that you can hold behind your back while checking noises, that might be your roommate.
I get the warm and fuzzies at around 200 grains, at 1200 fps, or, 230 grains
around 1100 fps, or, 250-260 grains at 1100 fps, or more.
Detonics picked the 200 grain load, at 1200 fps, using a Speer Flying Ashtray. The LEO shootings indicated it was VERY effective.
You should also know your bad guy. The great thing about LFN bullets at the above velocities is they don't have to expand to leave a very large hole, like 1" or more.
Deer:
LFN, hardcast, 1150 fps.
I had this conversation with my gunsmith, and he has two views. One is the .45 ACP just works.
Then he counters with that soft lead 260 grain bullets out of the .45 Colt, at 1000 fps might not penetrate, and or deviate from the path, missing vital organs. This is his argument for hardcast bullets.
Not sure I buy that, but, if you want a heavier soft lead, or jacketed bullet, then 275 grains might do the trick.
I think that John Browning had a pretty good idea with a 200 grain solid, at 950 fps. I don't think he would object to more velocity, but, the 1911 guns at the time didn't really have the strength that the guns today do, and probably wouldn't have held up to .45 Super loads.