My 625 gets more range time than any revolver I own, with the exception of my Ruger Bearcat. The little Ruger gets out more because I'm using it to teach my nephews and niece basic handgunning.
Although you didn't specify, I'm assuming that this revolver would be for personal defense and carried either on his person or in a planner/briefcase-type outfit. I would strongly advise against his buying any firearm with the thought of stashing it in his workplace, especially where burglary has been a recurring problem.
The 625 with any barrel length is a very large and relatively heavy handgun. Concealed carry is not its forte, although it can and has been done. Persons of larger than average stature would obviously have less trouble doing so. Most folks would find it easier to use one of the 'business concealment' options mentioned above for the best compromise of discretion and quick access with such a large weapon.
A slightly smaller option would be the Taurus 'Tracker' in .45 ACP. With the 4" barrel, it's just a tad heftier than a K-frame Smith. This size is a great deal easier for the average sized person to carry and conceal comfortably, IMO.
The .45 ACP gives up very little in the way of terminal performance with factory loads when used in a revolver. Those fat, heavy slugs are much less dependent upon projectile expansion for reliable SD perfromance than many other cartridges are.
Unless your cousin is a relatively experienced shooter, or willing to put in the time and effort to become one, he might well be better served by a mid-sized .38/.357 revolver such as the S&W K-frame, Ruger GP, Dan Wesson M-15, etc. Much easier and faster for the novice to gain an acceptable degree of competence with when regular, dedicated practice isn't likely to happen.