Here's what Buffalo Bore says about their .45 Colt hotloads, which offer even more oopmh than Cor-Bon's do:
"These Heavy .45 Colt loads are safe in all Ruger revolvers.
(includes Blackhawk, Super Blackhawk, Vaquero, Bisley, Redhawk)
These loads are also safe in all modern Model 1892 leverguns
as well as all Winchester & Marlin 1894's"
I take that to mean that these should be used in the Ruger only, or a Thompson/Center, or one of the listed leverguns.
I just got off the horn with Cor-Bon. The man there said the "+P Magnum" .45 Colt loads are safe for use in a Model 25-5, and that the 325 grain load is a lower-pressure round designed specifically for the smaller framed guns, like the Smith N-Frames.
Huh. Learn something every day. So, what the hell, I might buy a box of it. I bought my 25-5 to be a shooter, after all, not a trophy.
Of course, a lot of this stuff will accellerate the wear on your gun. But, if you can afford a lot of this stuff, you can afford another gun, too. Heh.
So, as near as I can tell, a 25-5 or equivalent will do fine with the Cor-Bon loads (especially the 325grn@1050fps loading), but a Ruger or Thompson Center is HIGHLY ADVISABLE for one of the Buffalo Bore loads. NONE of these loads should be fired in any Single Action Army or clone. (Ruger Blackhawks and Vaqueros are fine if you want a single action.)