Wow, I'm shocked that this thread has gone on so long. Why argue calibers? Why are you guys arguing over stuff that happened over 50 years ago. Its not relevant to the ammo used today so why bother. Lets talk reality not theoretical nonsense.
I say go and check any data or study you want and then you will reach the conclusion stated in my other post on this thread. THERE IS NO HANDGUN CALIBER THAT CAN GUARANTEE A ONE SHOT STOP.
With that premise in mind, go find a gun that fits your hand in a caliber that you shoot well, then practice, practice, practice. Rapid continuous shooting is the name of the game. Not single shots, not double taps, not Mosambique drills. But continuous rapid, on target shots. Hopefully you will never have to use deadly force to defend yourself or your family. But if you do, keep shooting until the threat is no longer a threat.
For what its worth one of the most deadly rounds I've seen is the 38 +p 158 gr lead semi wad cutter HP commonly called the metro (Metro-Dade) or FBI load but people don't want to believe that.