Gun Master, I have the same issues with arthritis (almost 70 years seems to do that to ya). I've tried a few different guns, but finally settled on the SIG P938.
While its more of a 911 style gun, its is a very good size for pocket carry, and the slide is very smooth to operate (I have a Shield that I simply cannot operate the slide on). The 938 is a very well made little gun and very accurate (look for one that was born in late 2013 or 2014, the early ones had some issues).
For little guns, I've had Kahrs, Kel-Tecs, two LC9s, a Shield, and an XDs. Only the P938 has stayed. In fact, I seldom carry anything bigger anymore. I can pop the 938 in my pocket or stick it in my waist band and I'm good to go.