I have a NEF in .22 Hornet, but I took a different route as far as loads. My main goal was a super quiet load for small game. With a miniscule amount of Unique, and a .22 air rifle pellet, the "Rabbit Magnum". It is both quiet and accurate. Very accurate. Then I just load a 55 grain FMJ for wolf and cougar repellent, using IMR4227. Not fussy about fine accuracy with that load, but it is not inaccurate. No problems with a 55 grain bullet tumbling. Seems to be perfectly stable at 100 yards.
My idea was a wilderness survival rifle, with the capability of larger game in an emergency, and defense against anything short of bears, or a bull moose, but it's kind of on the heavy side so I have not actually taken it trekking. That bull barrel weighs a bit. Something in the six pound range would be more ideal.
No, reloading for it has never been a problem.