I have an Aimpoint in a Larue mount.
I zeroed the Aimpoint at the range (50 yards with 75gr TAP). Later that day at home, I used the reddot to sight in the back up sight. I use the standard front sight base, with a Troy back-up, flup-up rear sight.
I just looked through the rear peep and centered the front post as you normally would. The dot was not on the tip of the post. It was a little high and a little to the left. So I adjusted the sights so that the dot and post line up perfectly, assuming you're looking through the center of the peep and have the post centred in the view properly.
This will get you very, very close, but not perfect. Definately close enough for human targets out to 200 yards though. It is good enough for practical use, but if you are picky like me, you want to get it perfect. When at the range, it might take 1 click of adjustment to get it just right. The zeroing with reddot is a great way to save time. Instead of having to shoot a few groups, it should only take (for a dirty barrel) 1 group to get it 100% on.
If your vision is good, you can be more precise with irons than an Aimpoint dot...