I've found that my CZ 452, stock, shoots awesome. A little slower on follow-up shots than a semi, but it shoots as well as any other .22LR's I've ever shot.
Personally, if I want to dump .22 size holes as fast as I can, I use my 5.56.
As far as people say .22LR is not an accurate round, 100+ yards in the wind hitting bottle caps and the rims of shotgun shells is pretty good. Golf balls aren't even a challenge.
Semi's can be picky on ammo, with feeding issues particularly. Some are picky about all brands of ammo except a single one. Some are just as reliable as a bolt. And they vary, serial # to serial #.
Do some research. Decide if you want to shoot irons or scoped, semi (magazine or tube), lever, pump, bolt. Decide how much you want to spend. Savage and CZ get compared a lot. The fit and finish on the CZ is nicer than many rifles, while Savage spends all their money on the barrels. I prefer a blend of both, so I went with a CZ. I couldn't find the perfect scope, so I ended up with a Nikon Omega, with BDC no less. But it has worked out perfect, for me. And then buy a handful more, just to 'check' to make sure that you have made the right choice(s). I'm looking forward to sitting down with my son and my father and uncle and playing with a dozen or so different .22's this summer, both pistols and rifles.
MY CZ hasn't minded any of the dozen or so brands of ammo I've fed it. The only issue I've had was when someone else was shooting it, they half-stroked the bolt (didn't chamber) and then pulled back without seating, then tried to stroke again. The only change with ammo was slight movement in POI.
And btw, I've found that tweaking the torque on the barrel and action lug does as much to change POI as changing the ammo brand. Something about barrel harmonics and the way the CZ 'cheats' on free floating the barrel.
Sorry for the wall of text. I've really enjoyed my .22's while recovering from surgery. As I'm still recovering a year later, I can see a strong improvement with both centerfire pistols and rifles.
Basics are basics, and there are few things like a .22 for working on basics. I've seen an improvement on all my own guns. I even got better on guns that I haven't ever touched before. Like a friend's 7mm or 1911. A few thousand rounds of .22 is a good deal cheaper than any other caliber. And, a few thousand rounds of .22 stores easier than uh... anything I can think of.