Another problem is what was called repetitive motion syndrome, now referred to as carpal tunnel syndrome (CTS). When bending the wrist the same way for extended periods, and especially with vibration or recoil-like movement, the nerve bundle leading through the carpal tunnel in the wrist joint is abraded by rubbing on said passage, causing nerve damage. This is sometimes evidenced by an electric-shock-like feeling and an involuntary release of what is gripped. It is worsened by continuing the repetitive process - and, some say, our diets. The mylos, or sheath, is said to be thin due to diet - adding certain supplements may help here - I think it has in my case. Surgery may be an aid, or a temporary relief, but the nerve damage is mostly permanent.
I developed CTS by holding woodturning chisels for hours as I turned the 12,000+ items I turned for my retirement hobby/avocation, now terminated, arts and craft business. It was just as I wound that down that I decided to start shooting a lot - mostly .45 Colts - and .454's. The weight of the revolver proved more troublesome than it's recoil. The trigger pull was worse - the AMT DA Backup's I had - and my neat little 1895 Nagants - both with 'tweaked' triggers over 20 lbs - hurt more than the 629MG stoked with .44 Magnums. The key here is to break up your regimine - don't do the same thing continuously. Treat the ache with whatever OTC antiflammatory you can - maybe even sleep with wrist braces on. Get professional help before you loose feeling in your fingers, etc.
BTW, my .45 Colt-style heavy push form of recoil hurts less than the sudden recoil of a .44 Magnum. Both can be made more manageable with a better grip position and grip construction, the SRH and the new S&W .500 grips being examples of such an improvement.
Stainz