I've shot a 629 extensively in competition. My 629-6 has something over 12,000 rounds through it, though almost all .44 Spc. ("Extensively", compared to most .44 Mag owners. Not "extensively" as compared to dedicated revolver competitors.)
If this actually IS for pin shooting, and you're considering a purchase to help you shoot pin competition better, then you need to tailor your decision to what actually will help you do your best work in that game.
(What I mean here is, if you're just looking to buy a neat .44 Mag and you might like to shoot it in a few pin matches, the range of guns you might consider is larger than if you're looking for a BEST-for-you pin-killing machine.)
So my thoughts would be this:
1) Seriously, speed is the essence of the game. Yes, you need to be accurate, but the distances aren't great so any quality handgun should be well more precise than you need.
1a) The most important thing here is speed of recovery/follow-up. If you've watched the guys winning your pin shoots now their shots are one even-cadenced string at good speed. They aren't fumbling to reacquire sights, or worse re-acquire a solid firing grip, after each shot. Standard power .44 Mag loads aren't going to help you at all. The suggestion of sticking with .45 ACP is a very realistic one. However, you can handload .44 Mag or .44 Spc to do a super job at a power level that gives you quick and smooth transitions. (That will be closer to .45ACP than "Buffalo Evicerator" and "Grizzly Smasher" .44 Mag levels.)
1b) Second thing is fast transitions so consider carefully what gun gets you shooting level and swinging smoothly through the pins. If that's an 8+" barrel, ok, but that feels REALLY long and front-heavy to me. (Of course, mine's a 4".) See what the best shooters in your group or region are using.
2) Grip / ergonomics: People have really strong opinions about some of the Ruger grip shapes. Some can't stand the Redhawk frame, and aftermarket grips can't fix that very well. This is not a concern at all with S&W as you can get any grip you could want.
3) Durability: 'Most any form of competition requires lots of practice and lots of match shots. There is a worry that large revolvers don't hold up well to tons of high-speed firing as that smashes the bolts and cylinder notches together hard, wears the hand, and so forth. I knew that when I chose my 629 and decided I'd see how things went. Well, I can definitely tell that it's been shot a lot now, but it's still pretty tight and the notch-peening appears to have progressed to a point early on and then not gotten any worse. At 12-15,000 rounds I'm not ready to even consider sending mine in for a refit. Some say/believe that Rugers are stronger or more durable. I really can't say yes or no, but my 629 has been plenty durable enough for my uses. Some suggested Colt Anacondas. While I never believe the extremes of the rumored "fragility" of Colt's wheelguns, there's just no realistic way I'd be using an Anaconda in competition. The cost of fixing it if it breaks, cost of tuning it up when ever I do shoot it loose or the timing starts to go, scarcity of parts, and even the damage to collector value (considerable with any Colt) simply because of the dings and wear of heavy use would make that a completely unrealistic choice for me.
4) Recall that Desert Eagles need jacketed bullets. If you are shooting and practicing much, you aren't going to want to pay for jacketed bullets all the time, when a dead simple SWC or even full wad-cutter cast lead bullet will do the job perfectly.