When I first started reloading, I spent a couple of years trying to achieve accuracy by following the numbers. Using BHN for pressure calculations, chronographing loads etc, I was convinced that I could mathematically come up with that perfect load. Unfortunately, the science rarely translated into real world accuracy and reliability.
Now, I take the opposite approach and really under think this. I determine my OAL first by using the plunk test and use the longest OAL that passes the test and still fits in the mag. While I do at least look at SAAMI specs to make sure I am not egregiously doing something wrong, I have often found optimal loads that are both over and under those specs (OAL speaking). I then start my powder charge at the bottom of the load data and work up slowly until I get the best accuracy, keeping an eye out for pressure signs.
It doesn't make my head hurt as much and it works for me.