One downside to using a Polymer 80 frame is you are stuck using their front locking block rail which is NOT interchangeable with a Glock front locking block. Other than that all Gen 1-3 parts parts work in the P80 frames. With Polymer 80 yo do have a choice of either an unfinished frame (80%) or a 100% finished frame that must transfer through a FFL.
If you are wanting a frame that you can just drop the parts into without any work then go with any of the 100% finished aftermarket frames that are available. That being said, I would still contact Glock to see what they say. Glock might have you ship the pistol in for repair or replacement. We have seen Glock repair/replace older pistols without questions may times.