I like Blue dot in my 45 Colt loads. H110 works, but it's more for heavy bullets and/or atomic big loads. If you're also wanting to use a powder in 38 spec, blue dot can work in that. H110 won't. But, H110 is good for .357 and .44 loads.
I also use WC820. I don't care for it, simply because you have to do a lot of load development on each lot to figure out it's burn rate. My 8 lb jug was much closer to AA #9 instead of H110. I had some close calls, in Ruger guns, while experimenting with it. If you're not an experienced handloader, I'd recommend staying with the commerical stuff vs the milsurp pull down powders.