I think/know it does. And if you go from Mfg to mfg you really should re zero your rifle at the very least. Now I reload everything I shoot but rimfire, sometimes because it is just not available on the open market, sometimes because the cost on the open market is crazy, and always to get things as stable as possible.
A few years ago I bought a Savage 99 in 243....really fun little rifle.....this was pre covid so ammo existed. The wife is at walmart and I ask her to get a couple boxes of different 243 ammo, different makers different bullet weights, you know the drill. When possible I like to shoot some factory for a base line, then I will use my hand loads against that. At work so I don't have the numbers handy but I do remember one maker has FPS numbers over 100fps off from the average, and that rifle did not like that ammo as well.
That is only my first hand experience with a wide range of factory ammo. I tend to like old military guns so you generally don't have a lot of choices when it comes to 8mm Label.
One thing I will say is there is no factory load that shoots "better" in any of my rifles over my reloads. And with "better" I am talking group sizes.
Now there are some VERY good commercial ammo for different calibers out there, and you do pay for that.
I can't speak to "quality" post covid during all the shortages, but it seems like the above poster comment would ring true, they are cranking them out as fast as they can, something is more likely to slip.