Just out of curiosity, does the same basic info hold true for Large Rifle also? Any problem going to a magnum primer instead of a standard one, regardless of caliber? Just back off the load a bit to test?
There's nothing on Hodgdon's site about H335 needing 'em for .223. Hodgdon does say to use 'em for .222 Rem Mag and other magnum cartridges for unknown reasons though.