With 5,000 primers through yours, you probably are better equipped than most to answer any simple questions, so it must be serious.
However, I have to start with the basics so I know what is happening.
The primer dispenser has two distinct motions to drop a single primer. The housing slides forward, then it cants down to actually drop the primer. Does it still make those same motions to drop a single primer (onto a padded surface rather than the priming arm for right now)?
Are the motions any different than they way they used to be?
The mechanism (when mounted on the press) needs to be (delicately and precisely) pressed forward all the way, and fully engaging the primer cup into the wedge-shaped recess BEFORE you cant the dispenser down to drop the primer. The primer cup must also be fully up in the recess. Both these relationships depend on precise adjustment of the dispenser position, but angular AND vertical (use shims to raise it if necessary).
It is easy to get complacent about the criticality of these basics, after 5,000 rounds. Did any of my suggestions turn on any lights?
If they seemed over-simplified, forgive me. Keep in mind that readers of all levels of familiarity with the dispenser are reading.
Let us know what you observe that might be a clue to the problem if my simple fixes do not help.
Lost Sheep