Well... is this going to be for CCW?
A large-frame snubby is going to be just that-- large, usually with a fairly fat cylinder. What I've found is once you get up in to the L-frame and N-frame (both larger than a K-frame) you're going to have to factor in the increased cylinder diameter, which can cause printing. That's why the small J-frames are so popular, the cylinder is quite a bit smalerl than the other S&W frame size cylinders. Honestly for me, a revolver with a K-frame size cylinder is at the limit to where I can conceal it realistically, but I carry a J-frame as my EDC just because of how compact and concealable it truly is.
Keep in mind that a K-frame has the same grip dimensions as an L-frame, and the grips are usually interchangeable between the two. Not only that, but the trigger reach is also basically the same between the K/L frame guns, and can be adjusted with larger grips. With the K-frame though, you get a skinnier cylinder vs. the larger L-frame, and can still have 6 shots of .38 special or .357 magnum depending on model.
The N-frames are truly large guns... the have a larger grips frame than the K/L frames, and the trigger reach is slightly longer in general. They fit a large hand very well, but they are big guns, and typically on the heavy side if they're an all stainless or carbon steel model. An N-frame snub would be a real chore to conceal and carry all day...
If I were you OP, I'd try out some K-frame snubs. They can be had for good prices (model dependent) on the used market, I don't think S&W makes a K-frame snub anymore but I could be wrong. You could also try a Ruger Speed Six, a great gun that's roughly K-frame in size and weight. If going the S&W route, a Model 10 w/ 2" bbl, round butt (or square butt if it fits you better), with S&W factory magna stocks paired with a Tyler T grip adapter would be the cats pajamas for CCW for somebody who just can't paw a J-frame snub. Stoke it with Speer Gold Dot .38 special +P 135 grain Short Barrel loads and you've got a hell of a gun right there.
Whatever you decide, good luck!