I'm not a machinist and I don't play one on T.V., so take this for what it costs you. If the barrel/cylinder gap decreases to the binding point as the wedge is tapped home, the barrel is pivoting at the only place it touches the frame, at the bottom where the two pins protrude. That pivoting can only happen if there is space enough at the front of the cylinder arbor to allow the wedge to pull the barrel rearward beyond where it needs to go. If that's happening it can be remedied by more length on the arbor or less depth in the barrel's arbor hole. I would be tempted to put some J.B. Weld on the front of the arbor and file it to the proper fit when it dries. You should be able to push your barrel wedge all the way in with the arbor bottoming on it's hole at the same time the frame/barrel joint is tight.
The problem with an arbor being too long can be more difficult to fix, depending on how bad it is. Pohill's shim is one way to get both bottoming out at the same time. Another way is by deepening the barrels arbor hole or shortening the arbor end. Since you don't want to modify the wedge slot on the barrel, the wedge slot in the arbor probably would need to be filed longer at the rear and filled in at the front. Also, it's possible to set the arbor deeper into the recoil shield, I suppose, but I would be beyond my depth trying that. I had an old brass framed revolver in which the arbor threaded into the recoil shield without any locking provision. I could thread it in as deeply as it needed to be with the slot lining up every half turn.
Steve