Yes you can, but....
Oughtsix, you need a lubrisizer. Its a great little gizmo. Mine is a Lyman 450. RCBS, Saeco, and some others make them too. You buy sizer dies for the diameter you want, a top punch that fits the bullet nose you're using, and some bullet lube. Then simply set the bullet in the die, pull the handle shoving the bullet down into the die (squishing it down in diameter), then screw a little tension on the lube tube and it squirts the grooves in your bullet full of lube, push the handle back up bringing the newly sized and lubed bullet back to you.
New lubrisizers...hmmm... probably in the $75 range. Dies about $20, top punch $8, lube $3 a tube (I use 50/50 candle wax and toilet bowl ring. Candles from garage sales dirt cheap, toilet bowl rings from Home Depot real cheap. Melt them together in a double boiler.).
For .45 Colt are you sure you want to go to .451 or .452? I suggest you slug your barrel, mic your chamber throats. Good chance your barrel will be .451 to .452, your throats might be .452 in which case you'll want to size to .454. Always run cast bullet diameters .002 inch bigger than throat diameter. Ideally your barrel diameter will be smaller than throat diameter, this will keep leading problems in check.
I believe you'll do fine sizing .459 cast bullets down to .454 or .452. Thats only .005 or .007 on a large diameter bullet, and you'll be shooting them in a revolver. Just don't expect 1" groups at 100 yards. Expect 3 inch groups at 25 yards and you'll be happy.
If you get the lubrisizer stuff, spend another $65 for molds, $30 for mold handles, $5 for ladel, $15 for plumbers lead pot, coleman stove at garage sale $?, stop by your tire store for some wheel weights and cast your own. I do.