One the one hand, it seems not.
Ruger says the extra poundage is necessary for reliable ignition with .22 rimfire ammo.
On the other hand, I have a S&W 317 .22RF that took both hands & three fingers to shoot DA.
I replaced the spring with a Wolff reduced power centerfire spring, and it dropped the DA pull by at least 1/3.
And it is still 100% reliable with any brand of .22 ammo I have shot in it in the last 10 years.
I guess the only sure way to find out is get a centerfire LCR mainspring and try it.
rc