San Francisco has long been the primary enemy of the RKBA in the state of CA, long before the rest of the state started to go downhill.
In the 1980s and before the state was actually quite conservative, but San Francisco has been nutty since the counter culture movement of the 1960s.
I believe a huge part of it is because it became a beacon for everything that didn't fit in elsewhere in the nation. From the minor to the really extreme beliefs and values. San Francisco attracted tons of people abandoning traditional values and was the primary place people could go and not be ostracized for it, and as such had a giant gaping lack of homogeneity. The result was a lot of problems that were not common in the rest of the nation. The solution? Endless laws to compensate.
They are anti-gun and have a culture of adding non stop regulation to solve problems. This has made it the third in lawyers per capita as well, behind only Washington D.C. and New York City. A city of lawyers to craft regulations and argue with regulations.
They actually voted to ban handguns in the city some years ago (overturned by the state) and the people of the city voted to make handguns illegal.
A huge excess of political power flows from San Francisco, it seems to get to speak for the entire Bay Area even though it has less than 1 million people, and most of it is so expensive it has long been gentrified so most low income criminals don't live in the area (Oakland next door is a whole different matter.)
My experience is that it has long wielded disproportionate power being almost equal to the level of Los Angeles, while being far smaller.
A lot of the top politicians including all of our recent senators (who are behind a lot of national anti-gun bills) in the US congress come from this disproportionately powerful city (Kamala Harris was the district attorney for San Francisco.)
Since the 1980s the state as a whole has shifted, but San Francisco has been the worst before Ronald Reagan was governor and the rest of the state knew it was quite different than most of the state.
Since then the mass influx of migrants has shifted the demographics and political field of all of California, and now San Francisco tries to take the lead in directing where the state goes.
Gov Moonbeam has California in a Death spiral.
Actually while he is not a huge RKBA supporter, he actually has vetoed a lot of the anti gun legislation that otherwise passed in California.
Some of the latest anti gun laws he signed last year he had previously vetoed a couple times.
He was actually holding back some of the tide, that is how bad the state is.
Only national level protections for the RKBA will protect Californians and keep California gun laws from setting a precedent for what is not considered a violation of the 2nd Amendment for the entire nation. Ignore CA at your own peril, it just make take another 20 years to reach you.
