I havent specifically patterned any to compare, but the 2" guns seem to work quite well for shot loads. I mostly load my own with the Speer capsules in 38 and 44 with No 12 shot and whatever their recommended loads are for Unique, and buy the ones for autos. Be sure you crimp them enough, a friend related that he was shooting a very large rattlesnake in a neighbors yard that was hiding in a cactus and rocks I believe, and one shot capsule creeped forward after the first shot and tied up his gun. Ive never had it happen, I must crimp more.
So far, the handful of 45 auto, both Speer and the old crimped brass Remington loads have functioned fine in a couple 1911 Colts Ive tried them in, and the Speer 9mm shot loads have functioned fine in an older G19. If carrying the glock around, I tend to keep a spare magzine in my pocket loaded with shot loads rather than having one or two at the top of the mag and/or one chambered. If snakes are more of a potential issue, I like 44 shot loads in a Smith revolver. Simply more volume of shot, though the 38s seem to work pretty well.
Keep in mind, none seem to work very well past about 10 feet, 5 feet is much better. The patterns just get a hole in the middle and makes it harder to hit stuff with much shot.