A cursory Pubmed search for fellow HighRoaders
Ginkgo biloba
Alpha-lipoic acid
references below:
Egb761 is a standardized extract of Ginkgo
1: Am J Otol. 2000 Mar;21(2):161-7. Biologic activity of mitochondrial metabolites on aging and age-related hearing
loss. Seidman MD, Khan MJ, Bai U, Shirwany N, Quirk WS.
Acetyl-L-carnitine and alpha-lipoic acid reduce age-associated deterioration in
auditory sensitivity and improve cochlear function. This effect appears to be
related to the mitochondrial metabolite ability to protect and repair
age-induced cochlear mtDNA damage, thereby upregulating mitochondrial function and improving energy-producing capabilities.
1: Am Fam Physician. 2003 Sep 1;68(5):923-6. Ginkgo biloba.
Sierpina VS, Wollschlaeger B, Blumenthal M.
Ginkgo biloba is commonly used in the treatment of early-stage Alzheimer's
disease, vascular dementia, peripheral claudication, and tinnitus of vascular
origin.
2: Pharmacopsychiatry. 2003 Jun;36 Suppl 1:S44-9.
Magnitude of effect and special approach to Ginkgo biloba extract EGb 761 in
cognitive disorders. Le Bars PL.
In the early 70's, improvements in methodical procedures of extraction and
standardization of ginkgo preparation allowed the production of a highly
concentrated and stable extract (EGb 761) (definition see editorial) by the
company Dr. Willmar Schwabe, which could be systematically tested in scientific programs. Consequently, numerous studies have been undertaken and provided replicable outcomes to demonstrate its efficacy in human population. EGb 761 is currently registered as an ethical drug in more than 50 countries around the world, and is prescribed for a range of neurological and vascular disorders including dementia, arterial occlusive disease, retinal deficit, and tinnitus.
3: Otolaryngol Clin North Am. 2003 Apr;36(2):359-81.
Alternative medications and other treatments for tinnitus: facts from fiction.
Seidman MD, Babu S.
Review Article
4: Otol Neurotol. 2003 Jul;24(4):572-5. Antioxidants in treatment of idiopathic sudden hearing loss. Joachims HZ, Segal J, Golz A, Netzer A, Goldenberg D.
OBJECTIVE: Assuming that superoxide anion radicals (O(2)-) may play a role in
damage to the inner ear, the authors investigated the possible benefit of
vitamin E as an antioxidant in the treatment of idiopathic sudden hearing loss.
RESULTS: The recovery rate, calculated as hearing gain
divided by the difference in hearing level between the affected and unaffected
ear, was better than 75% in 41 of 66 (62.12%) patients. This rate was achieved in 26 (78.78%) patients in the study group treated with vitamin E, compared with 15 (45.45%) patients in the control group. CONCLUSIONS: Patients treated with the addition of vitamin E achieved better recovery than did the control patients. Further studies should be directed toward a better understanding of the role of antioxidants in idiopathic sudden hearing loss.
7: Auris Nasus Larynx. 2002 Oct;29(4):329-33.
The role of zinc in management of tinnitus.
Yetiser S, Tosun F, Satar B, Arslanhan M, Akcam T, Ozkaptan Y.
Our study could not confirm the high incidence of hypozincemia in patients with tinnitus as reported previously. Zinc therapy for 8 weeks presented no promising effect on tinnitus in three groups of patients and the difference between the rate of improvement in severity of tinnitus after zinc intake in patients with normal and low serum zinc level was not significant. Zinc supplement provided relief of tinnitus in some of the elder people who apparently had dietary zinc deficiency.
