I would concur with the suggestion that your friend try the Beretta 92. I have only moderately large hands and the 92 fills my hand very nicely. When I put Beretta factory walnut grip panels on it, the reach to the DA trigger was actually a bit too much, so that combination might work very well for someone with huge hands.
My GI model Springfield Armory 1911 had the original, very short GI issue trigger and I found it quite a bit too small for my hand. I had to change out the trigger for a longer one and put spacers under the grip panels. Since 1911s are so easy to modify, that would also be an option.
I haven't shot a CZ75 but have pawed over a few and they are very comfortable as well.
I recently shot a Sig P320 with a medium grip module and found it comfortable, so perhaps a P320 with the large grip module might be ideal for your friend. I also shot the HK VP9, found it a bit less comfortable than the P320, but I don't know what size backstrap or grip side panels it was sporting. Perhaps a VP9 with the largest backstrap and side panels would be a good fit?
Someone mentioned an FNH FNS. I recently shot an FNS-9 and found it to be a pretty good fit, so you might add that to the list.
My GI model Springfield Armory 1911 had the original, very short GI issue trigger and I found it quite a bit too small for my hand. I had to change out the trigger for a longer one and put spacers under the grip panels. Since 1911s are so easy to modify, that would also be an option.
I haven't shot a CZ75 but have pawed over a few and they are very comfortable as well.
I recently shot a Sig P320 with a medium grip module and found it comfortable, so perhaps a P320 with the large grip module might be ideal for your friend. I also shot the HK VP9, found it a bit less comfortable than the P320, but I don't know what size backstrap or grip side panels it was sporting. Perhaps a VP9 with the largest backstrap and side panels would be a good fit?
Someone mentioned an FNH FNS. I recently shot an FNS-9 and found it to be a pretty good fit, so you might add that to the list.