You are absolutely correct.
How a particular load performs in a pistol with tighter groove diameter, chamber and shorter leade may perform differently for another pistol or carbine with larger groove diameter, chamber and longer leade. With that said, there are certain loads that seem to shoot well regardless of the pistol/barrel. One load is 45ACP 200 gr SWC with 4.8-5.0 gr of W231/HP-38. Most people report this load to be very accurate in their pistols. Another load I use is 45ACP 200 gr SWC with 4.0 gr of Red Dot/Promo and with softer 12 BHN MBC Bullseye #1 200 gr SWC, it is accurate in various 1911s, M&P45 and even in my PT145 with oversized barrel.
While we can gauge the accuracy of any load with group size, for comparison with other powders, I conduct my accuracy tests along with known reference loads. For 9mm, it is 115 gr FMJ with 4.8 gr W231/HP-38 and for 45ACP, it is 200 gr SWC with 4.8-5.0 gr W231/HP-38. So if a new load produces smaller/larger groups than reference load, regardless of firearm used, I can "gauge" how accurate the load is comparatively. Also, if I am having a "bad range day" where I can't seem to group anything, shooting known reference load will help me determine if it's me or the new load.
When I tested Vectan Ba9.5 (Powder I have never used before), I first shot a reference group with W231/HP-38 and then shot the powder work up. For the picture of comparison shot group, I did not include the 3.6 gr Vectan Ba9.5 load because grouping was very poor -
https://www.thehighroad.org/index.p...ectan-ba-9-5-ba-9.817796/page-2#post-10519646
So without the W231/HP-38 reference load, I would not know how accurate the Vectan 4.1 gr load was in comparison to other powders but since I shot with my reference load, I could say the Vectan load was comparable to reference load in accuracy.
25 yard 10 shot groups with RMR 115 gr FMJ at 1.130" with 4.8 gr W231/HP-38 (Left), 3.9 gr Vectan Ba9.5 (Center) and 4.1 gr Ba9.5 (Right)
Here are 25 yard IMR Target groups - RMR 115 gr FMJ at 1.130" with IMR Target 4.5-4.6 gr (Left), 4.2-4.3 gr (Center) and 4.0-4.1 gr (Right). So in comparison to my reference load, 4.2-4.3 gr IMR Target load was comparable.
Keep in mind that most powders will produce smaller groups with higher powder charges. But IMR Target produced smaller group with mid range load data.
This is good example why we need to conduct full powder work up as accuracy node can sometimes occur not near the top.
For RMR 100 gr Hardcore Match RN (rated to 1500 fps) testing, I used 5.5 gr of W231/HP-38 loaded to 1.050" OAL (Hodgdon max charge) as reference to compare with Promo 4.5-4.7 gr (extrapolated from 2004 Alliant load data for Red Dot for 95 gr FMJ at 1.055" with 5.3 gr max charge). Had I just shot the Promo load, I would not have known whether the group was good or bad but since I had the HP-38 load to compare, I would deem the Promo group to be comparable to HP-38 -
https://www.thehighroad.org/index.p...n-9mm-40s-w-45acp.799231/page-3#post-10245856