Top Five Cartridges for Medium sized to Large Game?

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If I’m picking five cartridges to suit my hunting needs I could probably start and stop with the 30-06, but that’s no fun. 99% of my hunting is likely to be whitetail and wild pigs, so my cartridges choices will reflect that.

1. 308
2. 6.8 SPC
3. 6.5x55
4. 300 Win Mag
5. 257 Weatherby Magnum
 
30-30 for deer at closer ranges or in the brush.
7mm-08 for deer everywhere else.
30-06 for deer and larger.

That's only three but I can't advocate cartridges I don't feel a need to actually own. 7mm RM is on my short list to buy though. I would have included the 6.5 Grendel a year ago but it failed me twice last deer season at longer ranges so it's still on my naughty list. It does make a great sub 200 yard gun.
 
Top 5 for medium to big game? Define big... If we are talking just North America then been there/done that already with 1 rifle (30-06) and 1 slug gun (12 gauge) chambering but man-o-man is that ever boring. Truth be told that was simply a product of the time frame and geography (Land of Lincoln was slugs for deer, rifle was all trips to the Rockies up until a few years ago). Haven't been to Africa (yet) but will either get a 9.3x62, 375 H+H, or a 458 depending on what interesting rifle turns up beforehand.

These days though, I don't recommend new folks start with the -06 anymore. Bullets are much better and many rounds can come close to the same versatile performance with less recoil.
 
I live in Michigan
.243 for coyotes and can be used for deer in the Northern rifle zone.
.30-30 and .30-06 deer in the rifle zone.
.44 mag and .450 bushmaster for deer in the Southern "Shotgun only" zone because a few years ago they opened it up to some straight wall rifle cartridges.
 
These days though, I don't recommend new folks start with the -06 anymore. Bullets are much better and many rounds can come close to the same versatile performance with less recoil.
As much respect as I have for the good ol' 30-06, and I indeed used one for better than 20 years (early '80s thru early 2,000s) there were cartridges that offered virtually the same "versatile performance" with less recoil even way back when I started big game hunting in 1963. And I didn't need todays "better bullets" to do it either.
I myself started with Remington CoreLokt factory loads (150grs for deer, and 180grs for elk) in a 308 Winchester. Later on, sometime in the mid-70s, I bought myself a 270 Winchester and used 130gr Remington CoreLokts in it for deer, elk and pronghorns. In the early '80s I finally "stepped up" to a 30-06, and started using my own, handloaded 165gr Hornady BTSPs for everything.
I use my own handloads in my 308 Norma Magnum for all my big game hunting nowadays of course. But I could go back to a 308 Winchester if I wanted to, and I've considered doing just that - because at my age, the mountains have grown steeper and taller, and I could get myself a lightweight, short action, 20 to 22 inch barreled 308 Winchester that probably wouldn't kick any harder than my 8.5 lb. 308 Norma Magnum with its 25" barrel. And while it could be argued that a 20 inch barreled 308 Winchester is not quite as "versatile" as my 25" barreled 308 Norma Magnum for big game hunting anywhere in North America, it would be "versatile enough" for all of the big game hunting I'm going to do from here on out.;)
 
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Medium game like deer and elk.
6.5 of your choice
.30 cal of your choice

Big Game like Moose, larger bears, eland.
.375 H&H or Ruger
.338 Win or similar

Thick skinned dangerous game, like Cape Buffalo, hippo, elephant or such.

.375 H&H at a minimum
.404 Jeff, or up for tight cover hunting.
 
For deer, I like:

243 Winchester - As a bonus, it's a great varmint rifle. Not to mention real easy on the shoulder. I like 85 gr Sierras in mine for all-round work.
30-30 Winchester - For thick brush and close shots; not to mention they are usually in light, handy rifles. Recoil is minimal and out to about 150 yards, accuracy is pretty good.
30-06 - Because I've used it for the last 15 years and will probably continue to use it until my shoulder can't take the recoil. Never had anything walk off from it (yet).

Were I going for elk or larger, I'd go:

300 Winchester - I'd trust it to knock down just about whatever I'd be interested in shooting. The only downside is recoil.
35 Whelen - Because it's a classic... and I'm nostalgic.

Mac
 
The round this rifle fired, has taken care of everything on this continent, and is perfectly capable of continuing to do so.

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The 30-06 is accurate enough for all purposes out to 600 yards, which is about 300 yards beyond ethical shooting distances, in my opinion. There are three, 3 shot groups in there, plus one. We all know, three shot groups are the standard for accuracy.

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not finicky about powder choice, the wind moves the bullet more than powder changes

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lots of great rifles built in 30-06

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Unless you want a 270 Win, I don't see a need for another game cartridge.
 
He only asked for top 5. That would be #6 ;)

But to answer your question I did get rid of my .358 BLR last week. Gave it to my son who turned 18 on Wednesday. That’s been the plan for a long time.

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Passing on firearms is not like your getting rid of them it's just letting someone that appreciates the gun as much as you do enjoy it. :)
 
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