I've had good results using it in 308 3006 and 762 54r for subsonic cartridges. 2 or 3 moa out to 100 was very attainable in the 308. The Russian needed cast bullets to shoot, but that was a bore issue, not tb related. Wound up doing under 3moa pretty easily.
5.56 can be loaded down similarly in my experience.
I've also had good luck in a bolt action 300 whisper with very light 90ish grain bullets. Very quiet and as accurate as a good 22 once I got things worked out. The little xtp is quiet and effective on garden thieves. There is a light half jacket that is great too...
I hate to give any actual load data, but I'm fairly certain you could use it in your cartridge based on what Ive seen. The 308 needed around 10 or 11g tb with a 200ish class bullet to be around 1050fps. There is a fair amount of published data for tb, though I'm not sure about your specific cartridge.
My primary worry, when loaded properly, is that trail boss will stick a bullet, so I heavily favor cast messing with it in most cases.
As a rule, don't compress tb. It gets weird.
All that said, I think there are probably better powders for you to use for light loads, but tb has worked well for me and I feel fine with it as long as its used correctly. Do not get hung up on powder standardization. That is NOT why I'd ever grab trail boss.