I've used Titegroup in 45 colt for several years. It is like a bullseye type powder a little bit goes a long way, but it's designed so that case volume means almost nothing. IE minimun charge with no wading in the case and the velocity shot to shot is very consistant. Accuracy is very good in most guns i've shot it in from 9mm to 44 magnum. Almost no leading with cast lead bullets to. Yes you have to be more carefull about double charging, but you also get more shots per pound of powder.