My 642-2, with OEM boots, shoots coincident POI/POA at 7-12yd with both Remington R38S12 +P 158gr LHPSWC and Georgia Arms ballistically equivalent similar reloads, which are much less expensive. The Remingtons are made with softer lead - which is impressive against 2L pop bottles full of water when shot from the 642. Either load is a little stout. I also have 'plinked' the SPC targets with my Montana Gold 125gr JHP homebrews (over 4-4.2 gr Titegroup) - easier shooting, of course. Also tried - Zero Ammo's 148gr LWC 'target' load - milder shooting load suggested as protective round for the recoil sensitive.
I've shot >2,200 rounds through my 642 over the 5+ years I've had owned it. It is not a 'fun' shooter - my 4" 64-8 is far more fun to plink with.
Stainz