What is the most painless way of killing a heavily wounded mammal?

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Assume the animal’s brain more or less resembles that of an average sized mammal (similar in size and properties of the brain of homo sapiens sapiens). EDIT: Nothing is to be fallaciously extrapolated from this: See my response below.
You aim for the brain point blank, but what angle/impact point do you pick and what kind of round do you use:

A .410, 10, 12, or a 20 gauge slug or a .4 HydraShok AE or a generic .5 AE?

The objective is minimization of expected pain and time to death of the animal. Please establish a ranking on the previously mentioned projectiles based on the objective.

Best regards,

MOSFET-Engineer

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Temple shot, even if they are not yet wounded, works great for Big Bears and small calibers.
Caribou and such get it in the back of the head, between the ears, or in the ear if at a right angle, 'Pithed', right there.
 
1. 10 gauge slug
2. 12 gauge slug
3. 20 gauge slug
4. .410 gauge slug
4. .5 AE FMJ
5. .4 HydraShok AE

1. Rear
2. Side
3. Frontal

I think this is the answer.
 
Since it's already heavily wounded, you're going to have to go with whatever you have on you at the time if you want to expedite the end and minimize suffering. Unless you're planning on administering Chloroform while it waits for you to go search the gun cabinet for the perfect round.
 
Any high intensity load into the brain disrupts everything. But even if a critter does the hucklebuck from a .22 rimfire into the brain, remember that the brain has no nerves to act as pain receptors.
 
Seperate the head from body (as common when hunting the non mammal Dove) or just sever spinal cord either way transmission of neural signals between the head and body stop...no pain, unless the only wound was in the head. Should be over pretty quick though.
 
Assume the animal’s brain more or less resembles that of an average sized mammal (similar in size and properties of the brain of homo sapiens sapiens).
You aim for the brain point blank, but what angle/impact point do you pick and what kind of round do you use

since I would never approach a large wounded animal from the front it would a side or rear shot. any shotgun 12-10 gauge


The objective is minimization of expected pain and time to death of the animal.

If you're planning on hunting Bigfoot then I'd use a big bore rifle to anchor him then a large bore handgun for the Co Degaru
 
What is the most painless way...

Painless for whom? :D

Firing a 10 ga slug at anything, and especially anything up close, is likely to result in a lot of pain for me!

As many have said, a .22 rimfire is good enough if well placed. For those who have concerns about getting through the skull, well, a .38 then. Can't see a reason for anything more than that.

Oh: I assume by ".5 AE" you mean a .50 Action Express? But what's a ".4 Hydrashok AE"? :confused:
 
What is the most painless way of killing a heavily wounded mammal?



Shoot it with a gun that doesn't generate much recoil.
 
I hate to push this thread up because I already got my answer and I might incite some anger/aggressive responses by doing so.
First of all I want to thank everyone who gave a serious and relevant response.
Then, I want to address the charge that I’m a “troll” because I posted the content in other forums: My only intention was to get more answers, thus increasing my chances of getting a high-quality, competent answer.
In hindsight, I have to admit it does look a little suspect with the homo sapiens brain reference in there. I only wanted to signify that we’re talking about a big species (like a buffalo, bear or deer).
The extrapolation that I’m anti-gun person or attention-seeking troll, I don’t understand at all. Layman yes, but I respect the 2nd Amendment as one of the most important parts of the Bill of Rights because it defines freedom, responsibility and democracy.
 
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You are totally overthinking the task.
Shoot the wounded critter in the brain/base of brain with any of the stated rounds and it will not suffer. If the 1st round doesn't do the trick, apply another in a different spot.
 
Last deer season I shot a doe and it dropped when I walked to it I noticed it set up on its two front legs but couldnt move from midback down because of the shot placement in the spine I'm guessing. But took another shot straight through the temple and it didn't even twitch afterwards. Temple shots always word. But the brainstem is another good place to shoot if you can get in the right angle. Never try to shoot between the eyes, you'll always miss
 
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