Defense is a layered approach. Being unobtrusive and in the middle of the block is part of that. Making sure that the kids don't brag on the family treasures, and not parading signs of wealth in front of the world (OPSEC) is part of that. Minimizing entrances with no sightline to the street is part of that. Having active neighbors who watch out for other neighbors is part of that. Having watchdogs and/or an alarm system is part of that. Making doors and windows hard to force open is part of that. Having the means to defend the family with deadly force is the LAST part of that.
So the question and provided answers are backwards - my first line of defense starts way outside the boundaries of my house walls, and the LAST line of defense goes BOOM!
Oh, and if it matters - my last line of defense is a Benelli M2 and a Glock 23. My wife favors a Ruger SR9. God knows what the boys will pick up - could be anything. And if you make it past all of that, and the dogs don't et ya, my daughter (age group national champion last year in first degree black belt Tae Kwon Do sparring) and her middle brother will turn you into a human Wavemaster.