I go through pistols like a state college student goes through girlfriends, but my first pistol, a Beretta 92FS, has survived it all. Believe me, it takes more than nostalgia for me to hold onto something, so it's a good thing it's so darn good-looking, ergonomic, and reliable. 'Course, the fact that over time I've gotten up to 2" groups at 15 yards (using Weaver) with it helps.
My current sweetie-pie is my Sig 228, which when considering that I'm getting near to the same accuracy level as the Beretta, will probably be around for a long time. But overall, the Beretta has received the most of my attention in the past seven years.