Yes, and I've heard that H110/W296 loads do not perform well below charges listed in the manuals, but many manuals don't agree on what that charge might be, as you have noted.
I suspect the caution about not reducing loads more than 3 percent, was started when many reloaders insisted on using non magnum primers with these powders, in spite of the manufacturers warnings.
The inconsistent performance at lighter loads that I'm seeing is an indication of poor ignition, and it's not too far fetched to imagine squib loads with regular primers at very cold temperatures, or when powder position in shifted to the front of the case.
Because I know these loads are on the edge, I listen very carefully for any unusual report, and stay alert for any change in felt recoil, before firing the next round.
Load data varies all over the place, because lab standards were apparently never established for load testing, or were too expensive to implement.
One company will use test barrels, while another will use off the shelf firearms, to develop loads for the same bullet. Add to that the different methods of measuring pressure, temperature and altitude variations, different barrel lengths, different bore sizes, and it's a wonder we get anything right.
Bill