I have hunted with and shot most of the top brand bullets from 180, through 240gr from my 44. I have found through the years that the Remington 240gr JHP has been time and time again as accurate and reliable or more so than many of the higher priced comparisons.
I use 23grs of 296 with my Ruger for a mid 1300fps load. It has through the years taken several deer and many feral hogs, and from a good rest has shot several groups around 1" or so at 50 and 100yds, depending on if the scope was installed.
For whitetail, unless you hit something pretty solid your not going to see much expansion, but still in all the .429 diameter slug is going to produce a nice sized hole in both sides.
For an all around bullet, I believe it is hard to beat both price and performance wise.