Here's what I think, unless you really want to trade away your .45 I probably wouldn't. I've had my share of .45's and 10mm's and I'm not really sure it matters one way or the other. One thing to keep in mind with the .45 is that if you want a bit more power you could always run .45 Super (also 450 SMC). Even if you don't want to do that, the .45 ACP can certainly work so long as you're competent with it.
Will a 10mm kill something the .45 cannot? I don't really think so, and I know it's not an option you listed but the .40 is a great choice too and can be had in a smaller sized gun, like a G23 which will be smaller and lighter to pack around and will work just fine against whatever you may encounter. But back to .45 vs 10mm, I still have a 10mm around and sure it's a good cartridge but I'm not convinced it will actually "DO" anything the .45, or .40 for that matter, won't do just as well.
It seems to me that you're setup just fine with a .45 and and .41 Mag, and yeah the 10mm is pretty cool but I don't really think it's going to give you anything that you don't already have, plus if you haven't handled a G29 you might want to do so, I'm a Glock guy but the size of the 29/30 is horrible, I think.