See thread
Lipsey & Ruger…ask for a GP100 in 41 Magnum!!! https://www.thehighroad.org/index.php?threads/lipsey-ruger…ask-for-a-gp100-in-41-magnum.898006/ . Pay attention to this post:
This is significant! If S&W makes N-frame with .670" thread, and chambering it in 41 Magnum, 44 Magnum and even 45 Colt, 11/16" thread in 10 mm GP100 clearly indicates that Ruger already made design changes that will allow GP100 chambered not just in 41 Magnum, but also in 44 Magnum and 45 Colt. Sort of DA Flattop. Of course, GP100 cannot compare in strength with Redhawk and Super Redhawk, but I would say it is close, if not at least equal, to S&W N-frame.
Also
GP100, something old, something new and what we could expect? https://www.rugerforum.com/threads/...and-what-we-could-expect.298775/#post-2976470