I bought a very used M586, the previous owned shot PPC with it, said he fired about 40K of 148 LSWC with 2.7 Bullseye and Federal primers.
Federal primers are the most sensitive primer on the market, thin cups and special sensitive priming compound.
I took the thing out in 40ish weather and shot a 158 LSWC with 12.0 grains AA#9 (a ball powder) with WSP. The weather was cold, there were snow flakes in the air, it was overcast and the wind was blowing. The ammunition had been overnight in the bed of the truck.
I had misfires, no hangfires, and I had squibs with a load I tested in 103 F weather. I had rounds that were anywhere between full power and squib. My load was with a 158 LRN with 12.0 grains AA#9. I used WSP primers. AA#9 is a very fine ball powder. It shot just fine in warm weather.
One round left a bullet in the throat of the 586. The bullet stuck in the 586 throat had a column of crusty/clumped ball powder behind it. Ball powder was all over the mechanism, I had to get a paper towel and wipe it out from under the extractor star, cylinder recess. Luckily I had a long shafted screwdriver and was able to knock the lead bullet out of the throat and continue shooting.
As you can see, the primer looks fairly well smacked.
What I did was change to a factory new mainspring. Next time I took it out, the weather was 50ish and I had positive ignition and no squibs!
So, if you have a used pistol, I recommend changing mainsprings. CCI primers have thicker cups than other brands, that can be an aggravating factor. I am of the opinion that with a light or shallow firing pin strike you can break the primer cake in the primer without the primer going off. I have taken rifle primers that were well hit but would not ignite, put a primer on a stove burner and the primer went off. (It was under a frying pan). If your pistol is new, look to federal primers and stay away from ball powder.
M586