Things to watch out for:
The priming system. I works fairly flawlessly until it doesn't. Usually this is related to the primer "plunger" making a small dimple in the bottom of the press where it's supposed to get support to push the primer into the case. Hornady should have reinforced this area but did not. A cheapy fix is to put a quarter or nickel there as the coin will give more than enough support for the plunger. You'll know when you need to reinforce this area because your press will start requiring a lot of effort to properly seat a primer, or you'll start experiencing press lock-ups because a primer isn't fully seated (very annoying!). After you use the coin trick you'll realize how easy it is to properly seat a primer and wonder why you didn't listen to me earlier. If only my wife would take note.
Powder spills. Sometimes you'll forget to seat a primer at all and proceed to charge a case without a primer. This causes lots of powder to spill out all over the press and generally make a mess of things. Additionally, the press "clicks" into place whenever you raise and lower the ram, which will sometimes cause cases to spill their powder. If you use a Powder Cop or Lock-Out die, the foot that goes into the case to make sure the charge is correct will also accumulate and drop powder. The powder will get into tiny, tiny crevasses, like the little holes underneath the shell plate that allow it to move around on the ram. You may want to do a quick brush-down every 100 rounds or so. You'll know when your shell plate is off just slightly and your cases no longer align perfectly with your dies. The powder can also affect the priming system as there's not a whole lot of wiggle room in the primer shuttle for anything other than a primer.
Burrs and unsmooth parts. You'll want to take some fine grit sandpaper to areas like the bottom of the primer shuttle, primer plunger, and primer shuttle area. Hornady could have done a better job of making sure everything fits just right but it's relatively easy to fix. You also may want to use a tiny bit of lube (eg One Shot) or grease around the primer shuttle to make sure it moves freely and easily.
The ball handle that comes with the ram is also unsmooth and will tear up your hand. I again took some fine grit sandpaper to it and now it's tolerable. You may want to look at Inline Fabrication as they manufacture a better handle for the press.
The powder measure is pretty good but you'll definitely want the Hornady Micrometer for both pistol and rifle; it's a lot easier to adjust and have easily repeatable charges. The stock measure requires you to unscrew something and has absolutely no markings on it whatsoever. If you find a charge and stick with it and never load anything but that one weight, great! Otherwise, get the micrometer.
The powder through expander (PTX) is over complicated. Check out PowderFunnels and get one of their units, which will just require adjustment of the powder measure like any other die; no additional contraptions to adjust!
For what it's worth I had an LnL until we moved to Arizona. I now work ~4 miles from the Dillon HQ. My credit card company has a newfound love for me.