I've been using the pro disk for years and just switched to the drum for some applications. The infinite adjustability of the drum is nice (the adjustable charge bar for the disk is teh scuk - leaks like crazy, inconsistent drops). But if you're changing calibers/loads a lot, just having a note of which disk hole to use makes set up a breeze and avoids having to fiddle with adjustment. But a bunch of spare inserts for the drum, each left adjusted to the desired volume/weight, might fill the same purpose.
I've only fooled with the drum for pistol powder so far, and don't know whether the larger insert would be sufficient to charge, say, a .308 or .45-70 rifle cartridge (which is going to take the double-stack upgrade to the disk). That caveat aside, I think the drum is probably better, unless you're going to be switching loads and calibers a lot - although spare inserts for it may be cheap enough to work around that issue, too.
Of course, I'm only about 1,000 rounds into the drum. Can't say anything about longevity, which has good with the disk. Both are at least decent products.